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Anti-Phospho-BCL-XL (Thr47) antibody

Catalog Number:OM682218
OM682218
Discount Price
OM682218-100ul
100ul
Product Profile
Product Name Anti-Phospho-BCL-XL (Thr47) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Thr47
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol BCL2L1
Gene Synonyms BCLX
BCL2L
Bcl-X
PPP1R52
BCL-XL/S
Gene Full Name BCL2 like 1
Gene Summary The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
Alternative Names Apoptosis regulator Bcl X antibody
Apoptosis regulator Bcl-X antibody
Apoptosis regulator BclX antibody
B cell lymphoma 2 like antibody
B2CL1_HUMAN antibody
Bcl 2 like 1 protein antibody
Bcl X antibody
Bcl xL antibody
BCL XL/S antibody
Bcl xS antibody
Bcl-2-like protein 1 antibody
Bcl2 Like 1 antibody
Bcl2 related gene antibody
Bcl2-L-1 antibody
BCL2L antibody
Bcl2l1 antibody
BCLX antibody
BclXL antibody
BclXs antibody
DKFZp781P2092 antibody
PPP1R52 antibody
Protein phosphatase 1 regulatory subunit 52 antibody
Molecular Weight(MW) 26 kDa
Cellular Localization Cytoplasm,Cytoplasmic vesicle,Cytoskeleton,Membrane,Mitochondrion,Mitochondrion inner membrane,Mitochondrion outer membrane,Nucleus,Synapse.
Database Links
SwissProt ID Q07817
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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