ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Product Name | Anti-Phospho-NMDAR2B (Tyr1474) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr1474 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIN2B |
|---|---|
| Gene Synonyms | NR3 MRD6 NR2B hNR3 DEE27 EIEE27 GluN2B NMDAR2B |
| Gene Full Name | glutamate ionotropic receptor NMDA type subunit 2B |
| Gene Summary | This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017] |
| Alternative Names | AW490526 antibody EIEE27 antibody Glutamate [NMDA] receptor subunit epsilon 2 antibody Glutamate [NMDA] receptor subunit epsilon-2 antibody Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody Glutamate receptor ionotropic NMDA2B antibody Glutamate receptor subunit epsilon 2 antibody Glutamate receptor ionotropic NMDA2B (epsilon 2) antibody GRIN 2B antibody GRIN2B antibody hNR 3 antibody hNR3 antibody MGC142178 antibody MGC142180 antibody MRD6 antibody N methyl D asparate receptor channel subunit epsilon 2 antibody N methyl D aspartate receptor subtype 2B antibody N methyl D aspartate receptor subunit 2B antibody N methyl D aspartate receptor subunit 3 antibody N-methyl D-aspartate receptor subtype 2B antibody N-methyl-D-aspartate receptor subunit 3 antibody NMDA NR2B antibody NMDA R2B antibody NMDAR2B antibody NMDE2 antibody NMDE2_HUMAN antibody NME2 antibody NR2B antibody NR3 antibody |
| Molecular Weight(MW) | 166 kDa |
| Cellular Localization | Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Endosome,Lysosome,Membrane,Postsynaptic cell membrane,Synapse. |
| SwissProt ID | Q13224 |
|---|
ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
