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Anti-Phospho-SPHK2 (Ser387) antibody

Catalog Number:OM682291
OM682291
Discount Price
OM682291-100ul
100ul
Product Profile
Product Name Anti-Phospho-SPHK2 (Ser387) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser387
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SPHK2
Gene Synonyms SK 2
SK-2
SPK 2
SPK-2
Gene Full Name sphingosine kinase 2
Gene Summary This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Alternative Names SK 2 antibody
Sphingosine kinase 2 antibody
Sphingosine kinase type 2 antibody
SPHK2 antibody
SPHK2_HUMAN antibody
SPK 2 antibody
Molecular Weight(MW) 69 kDa
Cellular Localization Cytoplasm,Endoplasmic reticulum,Lysosome,Membrane,Mitochondrion,Mitochondrion inner membrane,Nucleus.
Database Links
SwissProt ID Q9NRA0
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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