| Product Name | Anti-Phospho-MEK1/2 (Ser221)[Ser222] antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser221/Ser222 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAP2K1/MAP2K2 |
|---|---|
| Gene Synonyms | MEL CFC3 MEK1 MKK1 MAPKK1 PRKMK1/CFC4 MEK2 MKK2 MAPKK2 PRKMK2 |
| Gene Full Name | mitogen-activated protein kinase kinase 1/mitogen-activated protein kinase kinase 2 |
| Gene Summary | The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008] |
| Alternative Names | Dual specificity mitogen activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 ERK activator kinase 1 MAP kinase kinase 1 MAP kinase/Erk kinase 1 MAP2K1 MAPK/ERK kinase 1 MAPKK 1 MAPKK1 MEK 1 Mek1 MEKK1 Mitogen activated protein kinase kinase 1 MKK 1 MKK1 MP2K1_HUMAN PRKMK1 Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1) Protein kinase mitogen activated kinase 1 Cardiofaciocutaneous syndrome CFC syndrome CFC4 Dual specificity mitogen activated protein kinase kinase 2 Dual specificity mitogen-activated protein kinase kinase 2 ERK activator kinase 2 FLJ26075 MAP kinase kinase 2 map2k2 MAPK / ERK kinase 2 MAPK/ERK kinase 2 MAPKK 2 MAPKK2 MEK 2 MEK2 Microtubule associated protein kinase kinase 2 Mitogen activated protein kinase kinase 2 Mitogen activated protein kinase kinase 2 p45 MKK 2 MKK2 MP2K2_HUMAN OTTHUMP00000165826 OTTHUMP00000165827 PRKMK 2 PRKMK2 |
| Molecular Weight(MW) | 43 kDa,44 kDa |
| Cellular Localization | Cytoplasm,Cytoskeleton,Membrane,Nucleus./Cytoplasm,Membrane. |
| SwissProt ID | Q02750 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
