| Product Name | Anti-Phospho-HDAC5 (Ser498) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser498 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HDAC5 |
|---|---|
| Gene Synonyms | HD5 NY-CO-9 |
| Gene Full Name | histone deacetylase 5 |
| Gene Summary | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | Antigen NY CO 9 antibody Antigen NY-CO-9 antibody HD5 antibody HDAC 5 antibody HDAC5 antibody HDAC5_HUMAN antibody Histone deacetylase 5 antibody NY CO 9 antibody |
| Molecular Weight(MW) | 122 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | Q9UQL6 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
