| Gene Symbol |
SIRT1
|
| Gene Synonyms |
SIR2 SIR2L1 SIR2alpha |
| Gene Full Name |
sirtuin 1 |
| Gene Summary |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
| Alternative Names |
75SirT1 antibody
hSIR2 antibody
hSIRT1 antibody
HST2 S. cerevisiae homolog of antibody
NAD dependent deacetylase sirtuin 1 antibody
NAD dependent protein deacetylase sirtuin 1 antibody
OTTHUMP00000198111 antibody
OTTHUMP00000198112 antibody
Regulatory protein SIR2 homolog 1 antibody
SIR1_HUMAN antibody
SIR2 antibody
SIR2 like 1 antibody
SIR2 like protein 1 antibody
SIR2 S.cerevisiae homolog-like 1 antibody
SIR2-like protein 1 antibody
SIR2ALPHA antibody
SIR2L1 antibody
Sirt1 antibody
SirtT1 75 kDa fragment antibody
Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) antibody
Sirtuin 1 antibody
Sirtuin type 1 antibody |
| Molecular Weight(MW) |
82 kDa |
| Cellular Localization |
Cytoplasm,Mitochondrion,Nucleus. |