| Product Name | Anti-Phospho-TORC2 (Ser275) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser275 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CRTC2 |
|---|---|
| Gene Synonyms | TORC2 TORC-2 |
| Gene Full Name | CREB regulated transcription coactivator 2 |
| Gene Summary | This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010] |
| Alternative Names | CREB regulated transcription coactivator 2 CREB-regulated transcription coactivator 2 CRTC2 CRTC2_HUMAN RP11-422P24.6 TORC-2 torc2 Transducer of CREB protein 2 Transducer of regulated cAMP response element-binding protein Transducer of regulated cAMP response element-binding protein (CREB) 2 Transducer of regulated cAMP response element-binding protein 2 Transducer of regulated CREB protein 2 |
| Molecular Weight(MW) | 73 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | Q53ET0 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
