| Product Name | Anti-Phospho-PFKFB3 (Ser461) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser461 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PFKFB3 |
|---|---|
| Gene Synonyms | PFK2 IPFK2 iPFK-2 |
| Gene Full Name | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| Gene Summary | The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016] |
| Alternative Names | 6 phosphofructo 2 kinase/ fructose 2 6 bisphosphatase antibody 6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 3 antibody 6-bisphosphatase antibody 6-P2ase 3 antibody 6-P2ASE brain/placenta-type isozyme antibody 6PF 2 K/Fru 2 6 P2ASE brain/placenta type isozyme antibody 6PF 2-K/Fru 2 6 P2ase 3 antibody 6PF-2-K/Fru-2 antibody F263_HUMAN antibody fructose 6 phosphate 2 kinase/fructose 2 6 bisphosphatase antibody Fructose-2 antibody Inducible 6 phosphofructo 2 kinase/fructose 2 6 bisphosphatase antibody iPFK 2 antibody iPFK-2 antibody IPFK2 antibody PFK/FBPase 3 antibody PFK2 antibody PFKFB3 antibody Renal carcinoma antigen NY REN 56 antibody Renal carcinoma antigen NY-REN-56 antibody uPFK 2 antibody |
| Molecular Weight(MW) | 60 kDa |
| Cellular Localization | Cytosol. Nucleoplasm. |
| SwissProt ID | Q16875 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
