| Product Name | Anti-Phospho-SHP2 (Tyr542)[Tyr546] antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr542/Tyr546 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTPN11 |
|---|---|
| Gene Synonyms | CFC NS1 JMML SHP2 BPTP3 PTP2C METCDS PTP-1D SH-PTP2 SH-PTP3 |
| Gene Full Name | protein tyrosine phosphatase non-receptor type 11 |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016] |
| Alternative Names | BPTP3 CFC JMML METCDS MGC14433 NS1 OTTHUMP00000166107 OTTHUMP00000166108 Protein tyrosine phosphatase 2 Protein tyrosine phosphatase 2C Protein tyrosine phosphatase non receptor type 11 Protein-tyrosine phosphatase 1D Protein-tyrosine phosphatase 2C PTN11_HUMAN PTP-1D PTP-2C PTP1D PTP2C PTPN11 SAP2 SH-PTP2 SH-PTP3 SH2 domain containing protein tyrosine phosphatase 2 SHP 2 SHP-2 Shp2 SHPTP2 SHPTP3 Syp Tyrosine-protein phosphatase non-receptor type 11 |
| Molecular Weight(MW) | 68 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | Q06124 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
