| Product Name | Anti-Phospho-Syntaxin 1A (Ser14) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser14 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STX1A |
|---|---|
| Gene Synonyms | STX1 HPC-1 P35-1 SYN1A |
| Gene Full Name | syntaxin 1A |
| Gene Summary | This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| Alternative Names | HPC 1 Neuron specific antigen HPC1 Neuron-specific antigen HPC-1 OTTHUMP00000174615 OTTHUMP00000174616 OTTHUMP00000174617 OTTHUMP00000174618 P35-1 STX1 STX1A STX1A_HUMAN SYN1A Syntaxin 1A (brain) Syntaxin 1A brain Syntaxin-1A |
| Molecular Weight(MW) | 33 kDa |
| Cellular Localization | Cell membrane,Cytoplasmic vesicle,Membrane,Secreted,Synapse,Synaptosome. |
| SwissProt ID | Q16623 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
