| Gene Symbol |
DNMT3A
|
| Gene Synonyms |
TBRS HESJAS DNMT3A2 DNMT3A-3 M.HsaIIIA |
| Gene Full Name |
DNA methyltransferase 3 alpha |
| Gene Summary |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016] |
| Alternative Names |
DNA (cytosine 5) methyltransferase 3 alpha DNA (cytosine 5) methyltransferase 3A DNA (cytosine-5)-methyltransferase 3A DNA cytosine methyltransferase 3A2 DNA methyltransferase 3 alpha DNA methyltransferase 3a DNA methyltransferase HsaIIIA DNA MTase HsaIIIA DNM3A_HUMAN DNMT 3a DNMT Dnmt3a DNMT3A2 M.HsaIIIA MCMT OTTHUMP00000201149 TBRS |
| Molecular Weight(MW) |
102 kDa |
| Cellular Localization |
Chromosome,Cytoplasm,Nucleus. |