| Gene Symbol |
ATG4B
|
| Gene Synonyms |
APG4B AUTL1 HsAPG4B |
| Gene Full Name |
autophagy related 4B cysteine peptidase |
| Gene Summary |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Alternative Names |
APG4 autophagy 4 homolog B APG4B ATG4 autophagy related 4 homolog B (S. cerevisiae) ATG4B ATG4B_HUMAN AUT like 1 cysteine endopeptidase AUT-like 1 cysteine endopeptidase AUTL1 Autophagin 1 Autophagin-1 Autophagy related 4B cysteine peptidase Autophagy related cysteine endopeptidase 1 Autophagy related protein 4 homolog B Autophagy-related cysteine endopeptidase 1 Autophagy-related protein 4 homolog B Cysteine protease ATG4B hAPG4B MGC1353 |
| Molecular Weight(MW) |
44 kDa |
| Cellular Localization |
Cytoplasm,Cytoplasmic vesicle,Endoplasmic reticulum,Mitochondrion. |