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OM682519
Discount Price
OM682519-100ul
100ul
Product Profile
Product Name Anti-Phospho-GRK2 (Ser685) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser685
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GRK2
Gene Synonyms BARK1
ADRBK1
BETA-ARK1
Gene Full Name G protein-coupled receptor kinase 2
Gene Summary This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
Alternative Names ADRBK1
Adrenergic beta receptor kinase 1
ARBK1_HUMAN
BARK
BARK1
Beta adrenergic receptor kinase 1
Beta ARK 1
Beta ARK1
Beta-adrenergic receptor kinase 1
Beta-ARK-1
FLJ16718
G protein coupled receptor kinase 2
G-protein coupled receptor kinase 2
GRK2
Molecular Weight(MW) 80 kDa
Cellular Localization Cell membrane,Cell projection,Cytoplasm,Membrane,Synapse.
Database Links
SwissProt ID P25098
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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