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OM682583
Discount Price
OM682583-100ul
100ul
Product Profile
Product Name Anti-Phospho-MAP4K4 (Ser801) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH
Modification p-Ser801
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MAP4K4
Gene Synonyms HGK
NIK
MEKKK4
FLH21957
HEL-S-31
Gene Full Name mitogen-activated protein kinase kinase kinase kinase 4
Gene Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Alternative Names FLH21957
FLJ10410
FLJ20373
FLJ90111
Hepatocyte progenitor kinase like/germinal center kinase like kinase
HGK
HPK/GCK like kinase
HPK/GCK like kinase HGK
HPK/GCK-like kinase HGK
KIAA0687
M4K4_HUMAN
MAP4K4
MAPK/ERK kinase kinase kinase 4
MEK kinase kinase 4
MEKKK 4
MEKKK4
Mitogen activated protein kinase kinase kinase kinase 4
Mitogen-activated protein kinase kinase kinase kinase 4
Nck interacting kinase
Nck-interacting kinase
NIK
Molecular Weight(MW) 142 kDa
Cellular Localization Cytoplasm.
Database Links
SwissProt ID O95819
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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