| Product Name | Anti-Phospho-RAD51 (Tyr54) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr54 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RAD51 |
|---|---|
| Gene Synonyms | RECA BRCC5 FANCR MRMV2 HRAD51 RAD51A HsRad51 HsT16930 |
| Gene Full Name | RAD51 recombinase |
| Gene Summary | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] |
| Alternative Names | BRCA1/BRCA2 containing complex subunit 5 BRCC 5 BRCC5 DNA repair protein RAD51 homolog 1 DNA repair protein rhp51 FANCR hRAD51 HsRAD51 HsT16930 MRMV2 Rad 51 RAD51 RAD51 homolog (RecA homolog E. coli) (S. cerevisiae) RAD51 homolog A RAD51 homolog RAD51 recombinase RAD51 S. cerevisiae homolog of RAD51_HUMAN RAD51A RECA RecA like protein RecA E. coli homolog of Recombination protein A |
| Molecular Weight(MW) | 37 kDa |
| Cellular Localization | Chromosome, Cytoplasm, Cytoskeleton, Mitochondrion, Nucleus. |
| SwissProt ID | Q06609 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
