| Gene Symbol |
RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6
|
| Gene Synonyms |
RSK HU-1 RSK1 p90Rsk MAPKAPK1 MAPKAPK1A CLS RSK HU-3 RSK2 MRX19 ISPK-1 XLID19 p90-RSK2 pp90RSK2 MAPKAPK1B S6K-alpha3 RSK HU-2 RSK3 p90RSK2 p90-RSK3 pp90RSK3 MAPKAPK1C S6K-alpha S6K-alpha2 RSK4 RSK-4 p90RSK6 PP90RSK4 S6K-alpha-6 |
| Gene Full Name |
ribosomal protein S6 kinase A1/A3/A2/A6 |
| Gene Summary |
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Alternative Names |
90 kDa ribosomal protein S6 kinase 3 CLS HU 3 HU2 HU3 Insulin stimulated protein kinase 1 Insulin-stimulated protein kinase 1 ISPK-1 ISPK1 KS6A3_HUMAN MAP kinase activated protein kinase 1b MAP kinase-activated protein kinase 1b MAPK activated protein kinase 1b MAPK-activated protein kinase 1b MAPKAP kinase 1b MAPKAPK 1b MAPKAPK-1b MAPKAPK1B Mental retardation X linked 19 MRX19 OTTHUMP00000023036 p90 RSK2 p90 RSK3 p90-RSK 3 p90RSK3 pp90RSK2 Ribosomal protein S6 kinase 90kDa polypeptide 3 Ribosomal protein S6 kinase alpha 3 Ribosomal protein S6 kinase alpha-3 Ribosomal protein s6 kinase ii alpha 2 Ribosomal S6 kinase 2 Rps6ka3 RSK RSK-2 RSK2 S6 kinase 2 S6K alpha3 S6K-alpha-3 90 kDa ribosomal protein S6 kinase 2 HU 2 KS6A2_HUMAN MAP kinase activated protein kinase 1c MAP kinase-activated protein kinase 1c MAPK-activated protein kinase 1c MAPKAP kinase 1c MAPKAPK-1c MAPKAPK1C Mitogen.activated protein kinase-activated protein kinase 1C p90 RSK3 p90-RSK 2 p90RSK |
| Molecular Weight(MW) |
83 kDa,84 kDa |
| Cellular Localization |
Nucleus, Cytoplasm,cytosol. |