| Product Name | Anti-Phospho-CDK5 (Tyr239) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr239 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDK5 |
|---|---|
| Gene Synonyms | LIS7 PSSALRE |
| Gene Full Name | cyclin dependent kinase 5 |
| Gene Summary | This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] |
| Alternative Names | Cdk 5 Cdk5 CDK5_HUMAN Cell division protein kinase 5 Crk6 Cyclin dependent kinase 5 Cyclin-dependent kinase 5 Protein kinase CDK5 splicing PSSALRE Serine threonine protein kinase PSSALRE Serine/threonine-protein kinase PSSALRE Tau protein kinase II catalytic subunit TPKII catalytic subunit |
| Molecular Weight(MW) | 33 kDa |
| Cellular Localization | Cell membrane, Cell projection, Cytoplasm, Membrane, Nucleus, Synapse |
| SwissProt ID | Q00535 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
