| Gene Symbol |
M6PR
|
| Gene Synonyms |
SMPR MPR46 CD-MPR MPR 46 MPR-46 CD-M6PR |
| Gene Full Name |
mannose-6-phosphate receptor, cation dependent |
| Gene Summary |
This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011] |
| Alternative Names |
46 kDa mannose 6 phosphate receptor 46 kDa mannose 6-phosphate receptor Cation dependent mannose 6 phosphate receptor Cation dependent mannose 6 phosphate receptor precursor Cation-dependent mannose-6-phosphate receptor CD Man 6 P receptor CD Man-6-P receptor CD MPR CD-M6PR CD-MPR FLJ32994 M6pr M6PR protein Man6PR Mannose 6 phosphate receptor (cation dependent) Mannose 6 phosphate receptor MPR 46 MPR46 MPRD MPRD_HUMAN Mr 46 000 Man6PR Small mannose 6 phosphate receptor SMPR
|
| Molecular Weight(MW) |
31 kDa |
| Cellular Localization |
Lysosome membrane |