| Gene Symbol |
HCK/LYN
|
| Gene Synonyms |
JTK9 AIPCV p59Hck p61Hck/JTK8 SAIDV p53Lyn p56Lyn |
| Gene Full Name |
HCK proto-oncogene, Src family tyrosine kinase/LYN proto-oncogene, Src family tyrosine kinase |
| Gene Summary |
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010] |
| Alternative Names |
AA407514 EC 2.7.10.2 FLJ26625 Hck 2 JTK 8 JTK8 Lck/Yes related novel protein tyrosine kinase LYN LYN proto oncogene Src family tyrosine kinase LYN_HUMAN ONCOGENE LYN p53Lyn p56Lyn Tyrosine protein kinase LYN Tyrosine-protein kinase Lyn V yes 1 Yamaguchi sarcoma viral related oncogene homolog Yamaguchi sarcoma viral (v yes 1) related oncogene homolog Bmk Hck 1 Hck HCK_HUMAN Hemopoietic cell kinase JTK9 p59-HCK/p60-HCK p59Hck p59HCK/p60HCK p61Hck Tyrosine protein kinase HCK Tyrosine-protein kinase HCK
|
| Molecular Weight(MW) |
60 kDa,59 kDa |
| Cellular Localization |
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Golgi apparatus, Lysosome, Membrane, Nucleus/Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus |