| Gene Symbol |
MTCN
|
| Gene Synonyms |
NMYC ODED MODED MPAPA N-myc FGLDS1 bHLHe37 MYCNsORF MYCNsPEP |
| Gene Full Name |
MYCN proto-oncogene, bHLH transcription factor |
| Gene Summary |
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
| Alternative Names |
bHLHe37 Class E basic helix-loop-helix protein 37 MODED mycn MYCN_HUMAN N myc N myc proto oncogene protein N-myc proto-oncogene protein Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene Neuroblastoma MYC oncogene NMYC NMYC proto oncogene protein ODED Oncogene NMYC pp65/67 V myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog v myc avian myelocytomatosis viral related oncogene neuroblastoma derived v myc myelocytomatosis viral related oncogene neuroblastoma derived
|
| Molecular Weight(MW) |
50 kDa |
| Cellular Localization |
Nucleus |