| Gene Symbol |
CTNNA1
|
| Gene Synonyms |
MDBS2 MDPT2 CAP102 |
| Gene Full Name |
catenin alpha 1 |
| Gene Summary |
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016] |
| Alternative Names |
Alpha E-catenin Cadherin associated protein 102kDa Cadherin associated protein Cadherin-associated protein CAP 102 CAP102 Catenin (cadherin associated protein) alpha 1 102kDa Catenin (cadherin associated protein) alpha 1 102kDa Catenin alpha 1 Catenin alpha-1 CTNA1_HUMAN CTNNA 1 Ctnna1 FLJ36832 FLJ52416 MDPT2 NY REN 13 antigen OTTHUMP00000224141 OTTHUMP00000224147 Renal carcinoma antigen NY REN 13 Renal carcinoma antigen NY-REN-13 |
| Molecular Weight(MW) |
100 kDa |
| Cellular Localization |
Cell junction,Cell membrane,Cytoplasm,Cytoskeleton,Membrane,Nucleus. |