| Gene Symbol |
ILK
|
| Gene Synonyms |
P59 ILK-1 ILK-2 p59ILK HEL-S-28 |
| Gene Full Name |
integrin linked kinase |
| Gene Summary |
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
| Alternative Names |
59 kDa serine/threonine protein kinase 59 kDa serine/threonine-protein kinase DKFZp686F1765 Epididymis secretory protein Li 28 HEL S 28 ILK 1 ILK 2 ILK ILK-1 ILK-2 ILK_HUMAN ILK1 ILK2 Integrin linked kinase 2 Integrin linked Kinase Integrin linked protein kinase Integrin-linked protein kinase p59 p59ILK |
| Molecular Weight(MW) |
51 kDa |
| Cellular Localization |
Cell junction,Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Membrane,Nucleus. |