| Product Name | Anti-Phospho-MKK4 (Ser257/Thr261) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser257/Thr261 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAP2K4 |
|---|---|
| Gene Synonyms | JNKK MEK4 MKK4 SEK1 SKK1 JNKK1 SERK1 MAPKK4 PRKMK4 SAPKK1 SAPKK-1 |
| Gene Full Name | mitogen-activated protein kinase kinase 4 |
| Gene Summary | This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Alternative Names | c Jun N terminal kinase kinase 1 C-JUN N-terminal kinase kinase 1 Dual specificity mitogen activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 4 JNK Activated Kinase 1 JNK activating kinase 1 JNK-activating kinase 1 JNKK JNKK1 MAP kinase kinase 4 Map2k4 MAPK ERK kinase 4 MAPK/ERK kinase 4 MAPKK 4 MAPKK4 MEK 4 MEK4 Mitogen activated protein kinase kinase 4 MKK 4 MKK4 MP2K4_HUMAN PRKMK4 SAPK ERK kinase 1 SAPK/ERK kinase 1 SAPKK 1 SAPKK1 SEK1 SERK1 SKK1 Stress activated protein kinase kinase 1 |
| Molecular Weight(MW) | 44 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | P45985 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
