This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Alternative Names
Cek 11 Developmental kinase 1 EBK EHK-3 EHK3 EK11 Embryonic brain kinase EPH homology kinase 3 EPH-like kinase 11 Epha7 EPHA7_HUMAN Ephrin receptor Eph A7 Ephrin type A receptor 7 Ephrin type-A receptor 7 hEK11 MDK 1 Receptor protein tyrosine kinase HEK 11 Tyrosine protein kinase receptor EHK 3