| Gene Symbol |
PHGDH
|
| Gene Synonyms |
NLS PDG PGD NLS1 PGAD PGDH SERA 3PGDH 3-PGDH PHGDHD HEL-S-113 |
| Gene Full Name |
phosphoglycerate dehydrogenase |
| Gene Summary |
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011] |
| Alternative Names |
3 PGDH 3-PGDH 3-phosphoglycerate dehydrogenase 3PGDH D-3-phosphoglycerate dehydrogenase EC 1.1.1.95 Epididymis secretory protein Li 113 HEL S 113 NLS NLS1 PDG PGAD PGD PGDH PGDH3 Phgdh PHGDHD Phosphoglycerate dehydrogenase SERA SERA_HUMAN |
| Molecular Weight(MW) |
57 kDa |