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OM683017
Discount Price
OM683017-100ul
100ul
Product Profile
Product Name Anti-Phospho-MCSF Receptor (Tyr923) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH
Modification p-Tyr923
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CSF1R
Gene Synonyms FMS
CSFR
FIM2
GPSC
HDLS
C-FMS
CD115
HDLS1
CSF-1R
BANDDOS
M-CSF-R
Gene Full Name colony stimulating factor 1 receptor
Gene Summary The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. [provided by RefSeq, Mar 2017]
Alternative Names C FMS
CD 115
CD115
CD115 antigen
CFMS
Colony stimulating factor 1 receptor
Colony stimulating factor I receptor
CSF 1 R
CSF 1R
CSF-1 receptor
CSF-1-R
CSF1 R
CSF1R
CSF1R_HUMAN
CSFR
EC 2.7.10.1
FIM 2
FIM2
FMS
FMS proto oncogene
FMS protooncogene
HDLS
M-CSF Receptor
M-CSF-R
Macrophage colony stimulating factor 1 receptor
Macrophage colony stimulating factor I receptor
Macrophage colony-stimulating factor 1 receptor
McDonough feline sarcoma viral (v fms) oncogene homolog
MCSFR
Oncogen FMS
Proto-oncogene c-Fms
V-FMS McDonough feline sarcoma viral oncogen homolog
formerly
Molecular Weight(MW) 108 kDa
Cellular Localization Cell membrane,Membrane.
Database Links
SwissProt ID P07333
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
validation
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