| Gene Symbol |
CDC25A
|
| Gene Synonyms |
CDC25A2 |
| Gene Full Name |
cell division cycle 25A |
| Gene Summary |
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names |
Cdc 25a CDC25A CDC25A2 CDC25A2 CAG isoform Cell division cycle 25 homolog A (S. pombe) Cell division cycle 25A Cell division cycle 25A isoform a Cell division cycle 25A isoform b D9Ertd393e Dual specificity phosphatase Cdc25A M phase inducer phosphatase 1 M-phase inducer phosphatase 1 MGC115549 MPIP1_HUMAN |
| Molecular Weight(MW) |
59 kDa |
| Cellular Localization |
cytoplasm, cytosol, nucleoplasm, nucleus. |