| Product Name | Anti-Phospho-MKK7 (Thr275) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Thr275 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAP2K7 |
|---|---|
| Gene Synonyms | MEK MKK7 JNKK2 MEK 7 MAPKK7 PRKMK7 SAPKK4 SAPKK-4 |
| Gene Full Name | mitogen-activated protein kinase kinase 7 |
| Gene Summary | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Alternative Names | c-Jun N-terminal kinase kinase 2 Dual specificity mitogen activated protein kinase kinase 7 Dual specificity mitogen-activated protein kinase kinase 7 JNK activating kinase 2 JNK kinase 2 JNK-activating kinase 2 JNKK 2 Jnkk-2 Jnkk2 MAP kinase kinase 7 MAP2K7 MAPK/ERK kinase 7 MAPKK 7 MAPKK-7 MAPKK7 MEK 7 Mitogen Activated Protein Kinase kinase 7 MKK 7 MKK-7 MKK7 MP2K7_HUMAN PRKMK 7 PRKMK-7 PRKMK7 SAPK kinase 4 SAPKK-4 SAPKK4 Sek 2 Sek-2 Sek2 SKK4 stress-activated protein kinase kinase 4 |
| Molecular Weight(MW) | 47 kDa |
| Cellular Localization | Cytoplasm, Nucleus. |
| SwissProt ID | O14733 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
