| Gene Symbol |
PLK1
|
| Gene Synonyms |
PLK STPK13 |
| Gene Full Name |
polo like kinase 1 |
| Gene Summary |
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015] |
| Alternative Names |
Cell cycle regulated protein kinase PLK 1 PLK PLK-1 plk1 PLK1_HUMAN Polo like kinase 1 Polo-like kinase 1 Serine/threonine protein kinase 13 Serine/threonine protein kinase PLK1 Serine/threonine-protein kinase 13 Serine/threonine-protein kinase PLK1 STPK 13 STPK13 |
| Molecular Weight(MW) |
68 kDa |
| Cellular Localization |
Centromere, Chromosome, Cytoplasm, Cytoskeleton, Kinetochore, Nucleus. |