| Gene Symbol |
DSP
|
| Gene Synonyms |
DP DCWHKTA |
| Gene Full Name |
desmoplakin |
| Gene Summary |
This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| Alternative Names |
250/210 kDa paraneoplastic pemphigus antigen Desmoplakin I Desmoplakin II DP I DP II DPI DPII DSP KPPS2 PPKS2 |
| Molecular Weight(MW) |
332 kDa |
| Cellular Localization |
Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane, Nucleus. |