| Product Name | Anti-Phospho-DUSP1/MKP1 (Ser359) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser359 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DUSP1 |
|---|---|
| Gene Synonyms | HVH1 MKP1 CL100 MKP-1 PTPN10 |
| Gene Full Name | dual specificity phosphatase 1 |
| Gene Summary | The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017] |
| Alternative Names | CL 100 CL100 Dual Specificity Phosphatase 1 Dual specificity protein phosphatase 1 Dual specificity protein phosphatase hVH1 DUS1_HUMAN DUSP 1 Dusp1 HVH1 MAP kinase phosphatase 1 Mitogen-activated protein kinase phosphatase 1 MKP-1 MKP1 Protein tyrosine phosphatase CL100 Protein-tyrosine phosphatase CL100 PTPN10 Serine/threonine specific protein phosphatase VH1 |
| Molecular Weight(MW) | 39 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P28562 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
