| Product Name | Anti-Phospho-Tuberin/TSC2 (Ser1387) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser1387 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TSC2 |
|---|---|
| Gene Synonyms | LAM TSC4 PPP1R160 |
| Gene Full Name | TSC complex subunit 2 |
| Gene Summary | This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis. [provided by RefSeq, May 2022] |
| Alternative Names | FLJ43106 LAM OTTHUMP00000158940 OTTHUMP00000198394 OTTHUMP00000198395 PPP1R160 Protein phosphatase 1 regulatory subunit 160 tsc2 TSC2_HUMAN TSC4 TSC4 gene formerly TSC4 formerly Tuberin Tuberous sclerosis 2 Tuberous sclerosis 2 protein Tuberous sclerosis 2 protein homolog |
| Molecular Weight(MW) | 201 kDa |
| Cellular Localization | Cytoplasm, Lysosome, Membrane. |
| SwissProt ID | P49815 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
