| Product Name | Anti-Phospho-RapGEF1 (Thr1071) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Thr1071 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RAPGEF1 |
|---|---|
| Gene Synonyms | C3G GRF2 |
| Gene Full Name | Rap guanine nucleotide exchange factor 1 |
| Gene Summary | This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008] |
| Alternative Names | C3G C3G protein CRK SH3 binding GNRP CRK SH3-binding GNRP DKFZp781P1719 GRF 2 GRF2 Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) Guanine nucleotide releasing factor 2 Guanine nucleotide-releasing factor 2 OTTHUMP00000064558 Protein C3G Rap guanine nucleotide exchange factor (GEF) 1 Rap guanine nucleotide exchange factor 1 RAPGEF 1 RAPGEF1 RPGF1_HUMAN |
| Molecular Weight(MW) | 121 kDa |
| Cellular Localization | Endosome. |
| SwissProt ID | Q13905 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
