| Product Name | Anti-Phospho-Pim-1 (Tyr309) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr309 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PIM1 |
|---|---|
| Gene Synonyms | PIM |
| Gene Full Name | Pim-1 proto-oncogene, serine/threonine kinase |
| Gene Summary | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011] |
| Alternative Names | Oncogene PIM 1 Oncogene PIM1 PIM 1 pim 1 kinase 44 kDa isoform Pim 1 kinase pim 1 oncogene (proviral integration site 1) Pim 1 oncogene PIM PIM1 pim1 kinase 44 kDa isoform PIM1_HUMAN Pim2 PIM3 Proto oncogene serine/threonine protein kinase Pim 1 Proto-oncogene serine/threonine-protein kinase Pim-1 Proviral integration site 1 Proviral integration site 2 |
| Molecular Weight(MW) | 36 kDa |
| Cellular Localization | Cell membrane, Cytoplasm, Membrane, Nucleus. |
| SwissProt ID | P11309 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
