| Product Name | Anti-Phospho-LAT (Tyr191)[Tyr220] antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr191/Tyr220 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LAT |
|---|---|
| Gene Synonyms | LAT1 pp36 IMD52 |
| Gene Full Name | linker for activation of T cells |
| Gene Summary | The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Alternative Names | 36 kDa phospho tyrosine adapter protein 36 kDa phospho-tyrosine adapter protein 36 kDa phospho-tyrosine adaptor protein LAT 1 lat LAT_HUMAN LAT1 Linker for activation of T cells Linker for activation of T cells family member 1 linker for activation of T cells transmembrane adaptor Linker for activation of T-cells family member 1 p36 38 p36-38 pp36 |
| Molecular Weight(MW) | 28 kDa |
| Cellular Localization | Cell membrane,Membrane. |
| SwissProt ID | O43561 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
