| Gene Symbol |
BCL2
|
| Gene Synonyms |
Bcl-2 PPP1R50 |
| Gene Full Name |
BCL2 apoptosis regulator |
| Gene Summary |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| Alternative Names |
Apoptosis regulator Bcl 2 Apoptosis regulator Bcl-2 Apoptosis regulator Bcl2 AW986256 B cell CLL/lymphoma 2 B cell leukemia/lymphoma 2 Bcl-2 Bcl2 BCL2_HUMAN C430015F12Rik D630044D05Rik D830018M01Rik Leukemia/lymphoma B-cell 2 Oncogene B-cell leukemia 2 PPP1R50 Protein phosphatase 1 regulatory subunit 50 |
| Molecular Weight(MW) |
26 kDa |
| Cellular Localization |
Cytoplasm, Endoplasmic reticulum, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus. |