| Product Name | Anti-Phospho-Ku70 (Ser520) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser520 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | XRCC6 |
|---|---|
| Gene Synonyms | ML8 KU70 TLAA CTC75 CTCBF G22P1 |
| Gene Full Name | X-ray repair cross complementing 6 |
| Gene Summary | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
| Alternative Names | 5''-deoxyribose-5-phosphate lyase Ku70 5''-dRP lyase Ku70 70 kDa subunit of Ku antigen ATP dependent DNA helicase 2 subunit 1 ATP dependent DNA helicase II 70 kDa subunit ATP-dependent DNA helicase 2 subunit 1 ATP-dependent DNA helicase II 70 kDa subunit CTC box binding factor 75 kDa subunit CTC box-binding factor 75 kDa subunit CTC75 CTCBF DNA repair protein XRCC6 G22P1 Ku 70 Ku autoantigen p70 subunit Ku autoantigen 70 kDa Ku p70 Ku70 Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa Kup70 Lupus Ku autoantigen protein p70 ML8 Thyroid autoantigen 70kD (Ku antigen) Thyroid autoantigen Thyroid lupus autoantigen Thyroid lupus autoantigen p70 Thyroid-lupus autoantigen TLAA X ray repair complementing defective repair in Chinese hamster cells 6 X-ray repair complementing defective repair in Chinese hamster cells 6 X-ray repair cross-complementing protein 6 XRCC 6 Xrcc6 XRCC6_HUMAN |
| Molecular Weight(MW) | 70 kDa |
| Cellular Localization | Chromosome, Cytoplasm, Nucleus. |
| SwissProt ID | P12956 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
