| Gene Symbol |
SYK
|
| Gene Synonyms |
IMD82 p72-Syk |
| Gene Full Name |
spleen associated tyrosine kinase |
| Gene Summary |
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
| Alternative Names |
EC 2.7.10.2 kinase Syk KSYK KSYK_HUMAN p72-Syk p72syk Spleen tyrosine kinase Syk Tyrosine protein kinase SYK Tyrosine-protein kinase SYK |
| Molecular Weight(MW) |
72 kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Membrane. |