| Product Name | Anti-Phospho-CDK9 (Thr186) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Thr186 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDK9 |
|---|---|
| Gene Synonyms | TAK C-2k CTK1 CDC2L4 PITALRE |
| Gene Full Name | cyclin dependent kinase 9 |
| Gene Summary | The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008] |
| Alternative Names | C-2K CDC2 related kinase CDC2L4 Cdk 9 Cdk9 CDK9_HUMAN Cell division cycle 2-like protein kinase 4 Cell division protein kinase 9 CTK1 Cyclin dependent kinase 9 Cyclin-dependent kinase 9 PITALRE Serine/threonine-protein kinase PITALRE TAK Tat associated kinase complex catalytic subunit |
| Molecular Weight(MW) | 43 kDa |
| Cellular Localization | Cytoplasm, Nucleus. |
| SwissProt ID | P50750 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
