| Gene Symbol |
MCL1
|
| Gene Synonyms |
TM EAT MCL1L MCL1S Mcl-1 BCL2L3 MCL1-ES bcl2-L-3 mcl1/EAT |
| Gene Full Name |
MCL1 apoptosis regulator, BCL2 family member |
| Gene Summary |
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010] |
| Alternative Names |
Bcl 2 related protein EAT/mcl1 Bcl-2-like protein 3 Bcl-2-related protein EAT/mcl1 BCL2 related Bcl2-L-3 BCL2L3 EAT Induced myeloid leukemia cell differentiation protein Mcl 1 Induced myeloid leukemia cell differentiation protein Mcl-1 MCL 1 MCL1 MCL1-ES mcl1/EAT MCL1_HUMAN MCL1L MCL1S MGC104264 MGC1839 Myeloid Cell Leukemia 1 Myeloid cell leukemia ES Myeloid cell leukemia sequence 1 Myeloid cell leukemia sequence 1 BCL2 related Myeloid cell leukemia sequence 1 isoform 1 OTTHUMP00000032794 OTTHUMP00000032795 TM |
| Molecular Weight(MW) |
37 kDa |
| Cellular Localization |
Membrane, Single-pass membrane protein, Cytoplasm, Mitochondrion, Nucleus, nucleoplasm. |