Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of lipid transport; negative regulation of reactive oxygen species biosynthetic process; and negative regulation of transcription by RNA polymerase II. Located in nuclear speck. Biomarker of osteoarthritis. [provided by Alliance of Genome Resources, Jul 2025]
Alternative Names
FLJ16340 HBP 1 HBP1 HBP1_HUMAN High mobility group box transcription factor 1 HMG box containing protein 1 HMG box transcription factor 1 HMG box-containing protein 1