| Product Name | Anti-Phospho-IRF3 (Ser385) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser385 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IRF3 |
|---|---|
| Gene Synonyms | IIAE7 |
| Gene Full Name | interferon regulatory factor 3 |
| Gene Summary | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020] |
| Alternative Names | IIAE7 Interferon regulatory factor 3 IRF 3 IRF-3 IRF3 IRF3_HUMAN MGC94729 |
| Molecular Weight(MW) | 47 kDa |
| Cellular Localization | Cytoplasm, Mitochondrion, Nucleus. |
| SwissProt ID | Q14653 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
