| Product Name | Anti-Phospho-CaMKK2 (Ser511) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser511 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CAMKK2 |
|---|---|
| Gene Synonyms | CAMKK CAMKKB |
| Gene Full Name | calcium/calmodulin dependent protein kinase kinase 2 |
| Gene Summary | The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012] |
| Alternative Names | Calcium/calmodulin dependent protein kinase beta Calcium/calmodulin dependent protein kinase kinase 2 Calcium/calmodulin dependent protein kinase kinase 2 beta Calcium/calmodulin dependent protein kinase kinase beta Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase kinase beta CaM kinase kinase beta CaM KK beta CaM-kinase kinase 2 CaM-kinase kinase beta CaM-KK 2 CaM-KK beta CaMKK 2 CAMKK CaMKK beta CAMKK beta protein Camkk2 CAMKKB KKCC2_HUMAN |
| Molecular Weight(MW) | 65 kDa |
| Cellular Localization | Cell projection,Cytoplasm,Nucleus. |
| SwissProt ID | Q96RR4 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
