| Gene Symbol |
CYLD
|
| Gene Synonyms |
EAC MFT SBS TEM BRSS CDMT MFT1 CYLD1 CYLDI USPL2 FTDALS8 |
| Gene Full Name |
CYLD lysine 63 deubiquitinase |
| Gene Summary |
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Alternative Names |
BRSS CDMT Cyld CYLD gene CYLD_HUMAN CYLD1 CYLDI cylindromatosis (turban tumor syndrome) cylindromatosis 1 Deubiquitinating enzyme CYLD EAC HSPC057 KIAA0849 MFT MFT1 Probable ubiquitin carboxyl terminal hydrolase CYLD SBS TEM turban tumor syndrome Ubiquitin carboxyl-terminal hydrolase CYLD ubiquitin specific peptidase like 2 ubiquitin thioesterase CYLD Ubiquitin thiolesterase CYLD Ubiquitin-specific processing protease CYLD Ubiquitin-specific-processing protease CYLD USPL2 |
| Molecular Weight(MW) |
107 kDa |
| Cellular Localization |
Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Membrane,Microtubule. |