| Product Name | Anti-Phospho-ABCB11 (Ser690) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser690 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ABCB11 |
|---|---|
| Gene Synonyms | BSEP PGY4 SPGP ABC16 BRIC2 PFIC2 PFIC-2 |
| Gene Full Name | ATP binding cassette subfamily B member 11 |
| Gene Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008] |
| Alternative Names | ABC member 16 MDR/TAP subfamily ABC16 ABCB1 Abcb11 ABCBB_HUMAN ATP binding cassette sub family B (MDR/TAP) member 11 ATP binding cassette sub family B member 11 ATP-binding cassette sub-family B member 11 Bile salt export pump BRIC2 Bsep PFIC 2 PFIC2 PGY4 progressive familial intrahepatic cholestasis 2 Sister of P glycoprotein Spgp |
| Molecular Weight(MW) | 146 kDa |
| Cellular Localization | Cell membrane,Endosome,Membrane. |
| SwissProt ID | O95342 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
