| Product Name | Anti-Phospho-Cyclin H (Thr315) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Thr315 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCNH |
|---|---|
| Gene Synonyms | CAK p34 p37 CycH |
| Gene Full Name | cyclin H |
| Gene Summary | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010] |
| Alternative Names | 6330408H09Rik AI661354 AV102684 AW538719 CAK CAK complex subunit ccnh CCNH_HUMAN CDK activating kinase CDK activating kinase complex subunit Cyclin dependent kinase activating kinase cyclin dependent kinase activating kinase complex subunit Cyclin H Cyclin-H CyclinH MO15 associated protein MO15-associated protein p34 p36 p37 |
| Molecular Weight(MW) | 38 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P51946 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
