| Gene Symbol |
ANXA2
|
| Gene Synonyms |
P36 ANX2 LIP2 LPC2 CAL1H LPC2D ANX2L4 PAP-IV HEL-S-270 |
| Gene Full Name |
annexin A2 |
| Gene Summary |
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019] |
| Alternative Names |
Annexin A2 Annexin II Annexin II heavy chain Annexin-2 ANX 2 ANX2 ANX2L4 ANXA2 ANXA2_HUMAN arylsulfatase B CAL1H Calpactin I heavy chain calpactin I heavy polypeptide (p36) Calpactin I heavy polypeptide Calpactin-1 heavy chain chromobindin 8 Chromobindin-8 Epididymis secretory protein Li 270 HEL S 270 LIP2 Lipocortin II LPC2 LPC2D p36 P36 protein PAP-IV Placental anticoagulant protein IV Protein I |
| Molecular Weight(MW) |
39 kDa |
| Cellular Localization |
Basement membrane,Extracellular matrix,Secreted. |