| Gene Symbol |
PGR
|
| Gene Synonyms |
PR NR3C3 |
| Gene Full Name |
progesterone receptor |
| Gene Summary |
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015] |
| Alternative Names |
NR3C3 Nuclear receptor subfamily 3 group C member 3 PGR PR PRA PRB PRGR_HUMAN Progesterone receptor Progestin receptor form A Progestin receptor form B |
| Molecular Weight(MW) |
99 kDa |
| Cellular Localization |
Cytoplasm,Membrane,Mitochondrion,Mitochondrion outer membrane,Nucleus. |