| Product Name | Anti-Phospho-IRF4 (Tyr122/Tyr125) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr122/Tyr125 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IRF4 |
|---|---|
| Gene Synonyms | MUM1 LSIRF SHEP8 IMD131 NF-EM5 |
| Gene Full Name | interferon regulatory factor 4 |
| Gene Summary | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010] |
| Alternative Names | Interferon regulatory factor 4 IRF 4 IRF-4 Irf4 IRF4_HUMAN LSIRF Lymphocyte specific interferon regulatory factor Lymphocyte specific IRF Lymphocyte-specific interferon regulatory factor Multiple myeloma oncogene 1 MUM 1 MUM1 NF EM5 NF-EM5 NFEM5 PU.1 interaction partner Sfpi1/PU.1 interaction partner Transcriptional activator PIP |
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | Q15306 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
