| Gene Symbol |
HNRNPD
|
| Gene Synonyms |
P37 AUF1 AUF1A HNRPD hnRNPD0 |
| Gene Full Name |
heterogeneous nuclear ribonucleoprotein D |
| Gene Summary |
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008] |
| Alternative Names |
ARE binding protein AUFI type A AU-rich element RNA-binding protein 1 AUF AUF1 AUF1A Heterogeneous nuclear ribonucleoprotein D0 hnRNP D hnRNP D0 Hnrnpd hnRNPD0 HNRPD HNRPD_HUMAN P37 |
| Molecular Weight(MW) |
38 kDa |
| Cellular Localization |
Cytoplasm,Nucleus. |